Offspring genetic effects on maternal care

Disentangling prenatal and postnatal maternal genetic effects reveals persistent prenatal effects on offspring growth in mice.

Mothers are often the most important determinant of traits expressed by their offspring. These "maternal effects" (MEs) are especially crucial in early development, but can also persist into adulthood. They have been shown to play a role in a diversity of evolutionary and ecological processes, especially when genetically based. Although the importance of MEs is becoming widely appreciated, we k...

Genetic influences on maternal care.

The basis of social evolution in mammals is the mother-offspring relationship. It is also the primary and most important instance of indirect genetic effects, where genetic variation in one individual affects phenotypic variation among others. This relationship is so important in mammals that often the major factor determining the life or death of newborns is the environment provided by their m...

A RE-EVALUATION OF THE EFFECTS OF MATERNAL CARE ON OFFSPRING BEHAVIORAL DEVELOPMENT by

Effects of Maternal Alpha Methyldopa Administration on Memory of Rat Offspring during Growing Age

Background: Alpha Methyldopa (AMD) is a well-known treatment for the pregnancy induced hypertension and commonly used in several countries. Indeed the possible effect of AMD on the behavioral activities of offspring, whom are exposed during fetus period, has not been studied. The present study evaluated the possible effect of maternal administration of AMD on the rat offspring memory in the gro...

Phenotypic Effects of Maternal Hyperglycemia on Offspring Kidney Development

INTRODUCTION Diabetes is a heavily investigated disease as it is very detrimental to a vast majority of the human population. There has been a significant rise in cases of diabetes from 108 million people as of 1980 to 422 million cases as of 2014 [1]. This significant rise is another reason why this disease needs to be studied in order to work towards finding a cure and a solution. However, th...